Losonczy Lab

Department of Neuroscience at Columbia University Medical Center

Rita Nyilas

Rita Nyilas

Postdoctoral Research Fellow

e-mail: rn2428 AT cumc DOT columbia DOT edu

Research Interests: Cell type-specific modulation of neuronal coding during memory formation and distinct behavior-related neuronal activities in hippocampal networks.

 Education:

2010

Ph.D., Neuroscience

János Szentágothai Doctoral School of Neurosciences

Semmelweis Medical University, Budapest, Hungary

2003

M.Sc., Biology

Loránd Eötvös University, Budapest, Hungary

 

Positions:

2016-

Postdoctoral Researcher

Losonczy Lab

Columbia University

Principal Investigator: Attila Losonczy, M.D., PhD.

 

2010-2011

Postdoctoral Researcher

Laboratory of Molecular Neurobiology

Institute of Experimental Medicine, Budapest, Hungary

Principal Investigator: István Katona, Ph.D., D.Sc.

 

2006-2010

Assistant Research Fellow

Laboratory of Molecular Neurobiology

Institute of Experimental Medicine, Budapest, Hungary

Advisor: István Katona, Ph.D., D.Sc.

 

2003-2006

Graduate Student

Molecular Cell and Neurobiology Program

Loránd Eötvös University, Budapest, Hungary

Advisor: Gábor Juhász, Ph.D., D.Sc.

 

2000-2003

Student Research Technician

Research Group of Neurobiology of Hungarian Academy of Sciences

Loránd Eötvös University, Budapest, Hungary

Advisor: Gábor Juhász, Ph.D, D.Sc.

 

Awards:

2017

Rosztoczy Foundation Scholarship

2011

Academy Prize for Young Scientists, Hungarian Academy of Sciences

2009

Poster Presentation Award, Hungarian Neuroscience Society Annual Meeting

2008

Young Lecturer Prize, Hungarian Society for Microscopy Conference

2003

Second Prize, National Conference for Undergraduate Students, Szeged,                               Hungary

2002

Scholarship of the Hungarian Republic

2002

Student Excellence Award of the Faculty of Science, Loránd Eötvös University, Budapest, Hungary

 

Teaching Activity:

2003-2005

Graduate Teaching Assistant

Department of Anatomy, Cell- and Developmental Biology

Loránd Eötvös University, Budapest, Hungary

 

Presentations:

2007

Nyilas R, Urbán GM, Mackie K, Watanabe M, Freund TF and Katona I: Molecular Architecture of Endocannabinoid Modulation of Nociception in the Dorsal Horn of     the Spinal Cord. Symposium on “Cannabinoid Signaling in the Nervous System”, 17th Neuropharmacology conference, San Diego, USA

 

 Publications:

Dudok B, Barna L, Ledri M, Szabó SI, Szabadits E, Pintér B, Woodhams SG, Henstridge CM, Balla GY, Nyilas R, Varga C, Lee SH, Matolcsi M, Cervenak J, Kacskovics I, Watanabe M, Sagheddu C, Melis M, Pistis M, Soltesz I and Katona I (2015) Cell-specific STORM superresolution imaging reveals nanoscale organization of cannabinoid signaling. Nature Neuroscience, 18(1):75-86.

 

Ramikie TS, Nyilas R, Bluett RJ, Gamble-George JC, Hartley ND, Mackie K, Watanabe M, Katona I and Patel S (2014) Multiple mechanistically distinct modes of endocannabinoid mobilization at central amygdala glutamatergic synapses. Neuron, 81(5):1111-25.

 

Horváth E, Woodhams SG, Nyilas R, Henstridge CM, Kano M, Sakimura K, Watanabe M and Katona I (2014) Heterogeneous presynaptic distribution of monoacylglycerol lipase, a multipotent regulator of nociceptive circuits in the mouse spinal cord. European Journal of Neuroscience, 39(3):419-34.

 

Kato A, Punnakkal P, Pernia-Andrade AJ, von Shoultz C, Sharopov S, Nyilas R, Katona I, and Zeilhofer HU (2012) Endocannabinoid-dependent plasticity at spinal nociceptor synapses. Journal of Physiology-London, 590:4717-4733.

 

Gregg LC, Jung KM, Spradley JM, Nyilas R, Suplita II RL, Zimmer A, Watanabe M, Mackie K, Katona I, Piomelli D and Hohmann AG (2012) Activation of type 5 metabotropic glutamate receptors and diacylglycerol lipase-α initiates 2-arachidonoylglycerol formation and endocannabinoid-mediated analgesia. The Journal of Neuroscience, 32:9457-9468.

 

Takács E, Nyilas R, Szepesi Z, Baracskay P, Karlsen B, Røsvold T, Bjørkum AA, Czurkó A, Kovács Z, Kékesi AK and Juhász G (2010) Matrix metalloproteinase-9 activity increased by two different types of epileptic seizures that do not induce neuronal death: A possible role in homeostatic synaptic plasticity. Neurochemistry International, 56:(6-7)799-809.

 

Nyilas R, Gregg LC, Mackie K, Watanabe M, Zimmer A, Hohmann AG and Katona I (2009) Molecular architecture of endocannabinoid signaling at nociceptive synapses mediating analgesia. European Journal of Neuroscience, 29:1964-1978.

 

Pernia-Andrade AJ, Kato A, Witschi R, Nyilas R, Katona I, Freund TF, Watanabe M, Filitz J, Koppert W, Schüttler J, Ji G, Neugebauer V, Marsicano G, Lutz B, Vanegas H and Zeilhofer HU (2009) Spinal endocannabinoids and CB1 receptors mediate C-fiber-induced heterosynaptic pain senzitization. Science, 325:760-764.

 

Nyilas R, Dudok B, Urbán GM, Mackie K, Watanabe M, Cravatt BF, Freund TF and Katona I (2008) Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals. The Journal of Neuroscience, 28: 1058-1063.

 

Papp AM, Nyilas R, Szepesi Z, Lorincz ML, Takacs E, Abraham I, Szilagyi N, Toth J, Medveczky P, Szilagyi L, Juhasz G and Juhasz G (2007) Visible light induces matrix metalloproteinase-9 expression in rat eye. Journal of Neurochemistry, 103:(6) 2224-2233.

 

Kovacs Z, Kekesi KA, Bobest M, Torok T, Szilagyi N, Szikra T, Szepesi Z, Nyilas R, Dobolyi A, Palkovits M and Juhasz G (2005) Post mortem degradation of nucleosides in the brain: comparison of human and rat brains for estimation of in vivo concentration of nucleosides. Journal of Neuroscience Methods, 148:(1) 88-93.